abstract：:Stress is a multidimensional construct. To accurately represent stress physiology, multiple stress measures across multiple stress-related systems should be assessed. However, associations may be masked given that different systems underlie different time courses. Salivary cortisol and alpha-amylase (sAA) are reliable...

journal_title：Psychoneuroendocrinology

authors： Engert V,Vogel S,Efanov SI,Duchesne A,Corbo V,Ali N,Pruessner JC

更新日期：2011-10-01 00:00:00

abstract：:Chronic stress contributes to many neuropsychiatric disorders in which the HPA axis, cognition and neuro-immune activity are dysregulated. Patients with major depression, or healthy individuals subjected to acute stress, present elevated levels of circulating pro-inflammatory markers. Acute stress also activates pro-i...

journal_title：Psychoneuroendocrinology

authors： Girotti M,Donegan JJ,Morilak DA

更新日期：2011-09-01 00:00:00

abstract：:The relationships between positive emotional style and acute salivary cortisol and cardiovascular responses to laboratory stress tasks were examined in 40 young women (mean age=28.8 years). Positive emotional style (PES) was measured by aggregating daily positive mood rating scales over one week. Negative affect was a...

journal_title：Psychoneuroendocrinology

authors： Bostock S,Hamer M,Wawrzyniak AJ,Mitchell ES,Steptoe A

更新日期：2011-09-01 00:00:00

abstract：:The buffer hypothesis of the Job Demand-Control Model predicts that high levels of job control compensate for the negative effects of high job demands on well-being and health. Several studies have tested this hypothesis, but the results are far from consistent. The objective of this study was to test the buffer hypot...

journal_title：Psychoneuroendocrinology

authors： Häusser JA,Mojzisch A,Schulz-Hardt S

更新日期：2011-08-01 00:00:00

abstract：:High levels of cortisol, a sign of potential hypothalamic-pituitary-adrenal (HPA) axis dysregulation, have been associated with poor cognitive outcomes in older adults. Most cortisol research has focused on hippocampal-related abilities such as episodic memory; however, the presence of glucocorticoid receptors in the ...

journal_title：Psychoneuroendocrinology

authors： Franz CE,O'Brien RC,Hauger RL,Mendoza SP,Panizzon MS,Prom-Wormley E,Eaves LJ,Jacobson K,Lyons MJ,Lupien S,Hellhammer D,Xian H,Kremen WS

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Depressive patients often have altered cortisol secretion, but few studies have investigated genetic variants in relation to both cortisol secretion and depression. To identify genes related to both these conditions, we: (1) tested the association of single nucleotide polymorphisms (SNPs) in hypothalamic-pit...

journal_title：Psychoneuroendocrinology

authors： Velders FP,Kuningas M,Kumari M,Dekker MJ,Uitterlinden AG,Kirschbaum C,Hek K,Hofman A,Verhulst FC,Kivimaki M,Van Duijn CM,Walker BR,Tiemeier H

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Several studies have established links between thyroid gland dysfunction and mood disorders, in particular major depressive disorder (MDD). Preliminary evidence also suggests that thyroid hormone gene variants influence grey matter (GM) volume, which is reportedly altered in patients with MDD. This study test...

journal_title：Psychoneuroendocrinology

authors： Dixson L,Ridler K,Nichols TE,Saemann PG,Auer DP,Holsboer F,Muglia P,Matthews PM,Inkster B

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The dysfunction of hypothalamic-pituitary-adrenal (HPA) axis in major depression includes hyperactivity and reduced feedback inhibition. Atrial natriuretic peptide (ANP) is able to reduce the HPA-axis response to stress and has an anxiolytic effect in rodents and humans. We hypothesized that patients with de...

journal_title：Psychoneuroendocrinology

authors： Krogh J,Ströhle A,Westrin A,Klausen T,Jørgensen MB,Nordentoft M

更新日期：2011-06-01 00:00:00

abstract：:Opioid administration in males results in opioid-induced androgen deficiency which persists throughout the treatment. In adults, this quickly reverses once opioid administration is suspended. However, less is known about the duration of the effect following drug discontinuation in adolescents. Given the significant im...

journal_title：Psychoneuroendocrinology

authors： Hofford RS,Wellman PJ,Eitan S

更新日期：2011-06-01 00:00:00

abstract：:The incidence of chronic stress is frequently related to the development of psychiatric disorders like depression. The hypothalamic-pituitary-adrenal (HPA) axis is a major physiological system that mediates the stress response. Tight HPA axis regulation through negative feedback mechanisms is essential for health and ...

journal_title：Psychoneuroendocrinology

authors： Wagner KV,Wang XD,Liebl C,Scharf SH,Müller MB,Schmidt MV

更新日期：2011-05-01 00:00:00

abstract：:In the field of depression, inflammation-associated depression stands up as an exception since its causal factors are obvious and it is easy to mimic in an animal model. In addition, quasi-experimental studies can be carried out in patients who are treated chronically with recombinant cytokines for a medical condition...

journal_title：Psychoneuroendocrinology

authors： Dantzer R,O'Connor JC,Lawson MA,Kelley KW

更新日期：2011-04-01 00:00:00

abstract：:Early life stress is one of the best characterized risk factors for psychiatric disorders, including depression, and many animal models have therefore studied the long-term physiological and behavioural consequences of early life stress. In most approaches a very deterministic view of adverse experiences early in life...

journal_title：Psychoneuroendocrinology

authors： Schmidt MV

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Hypothalamus-Pituitary-Adrenal (HPA) axis dysregulation is often seen in major depression, and is thought to represent a trait vulnerability - rather than merely an illness marker - for depressive disorder and possibly anxiety disorder. Vulnerability traits associated with stress-related disorders might refl...

journal_title：Psychoneuroendocrinology

authors： van Santen A,Vreeburg SA,Van der Does AJ,Spinhoven P,Zitman FG,Penninx BW

更新日期：2011-02-01 00:00:00

abstract：:Arginine Vasopressin modulates complex social and sexual behavior by enhancing social recognition, pair bonding, and aggression in non-human mammals. The influence of Arginine Vasopressin in human social and sexual behavior is, however, yet to be fully understood. We evaluated whether Arginine Vasopressin nasal spray ...

journal_title：Psychoneuroendocrinology

authors： Guastella AJ,Kenyon AR,Unkelbach C,Alvares GA,Hickie IB

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Several studies have assessed the effects of training using patient simulation systems on medical skills. However, endocrine and psychological stress responses in a patient simulation situation and the relationship between stress reactivity and medical performance have been studied rarely, so far. METHODS:M...

journal_title：Psychoneuroendocrinology

authors： Keitel A,Ringleb M,Schwartges I,Weik U,Picker O,Stockhorst U,Deinzer R

更新日期：2011-01-01 00:00:00

abstract：:Poor adaptation to stress, alterations in cerebrovascular function and excessive brain inflammation play critical roles in the pathophysiology of many psychiatric and neurological disorders such as major depression, schizophrenia, post traumatic stress disorder, Parkinson's and Alzheimer's diseases and traumatic brain...

journal_title：Psychoneuroendocrinology

authors： Saavedra JM,Sánchez-Lemus E,Benicky J

更新日期：2011-01-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP), originally found in the cardiac atria, is also widely distributed in the central nervous system (CNS) and has been predominantly found in the hypothalamus and the pituitary gland. Previous in vitro and in vivo studies have provided evidence for an inhibitory control of ANP at all regu...

journal_title：Psychoneuroendocrinology

authors： Demiralay C,Jahn H,Kellner M,Yassouridis A,Wiedemann K

更新日期：2010-11-01 00:00:00

abstract：:Stress can affect the establishment and maintenance of social hierarchies. In the present study, we investigated the role of increasing corticosterone levels before or just after a first social encounter between two rats of a dyad in the establishment and the long-term maintenance of a social hierarchy. We show that p...

journal_title：Psychoneuroendocrinology

authors： Timmer M,Sandi C

更新日期：2010-11-01 00:00:00

abstract：:Modulation of the serotonergic (5-HT) neurotransmitter system arising from the dorsal raphe nucleus (DR) is thought to support the behavioral effects of swim stress, i.e., immobility. In vivo pharmacological and anatomical studies suggest that corticotropin-releasing factor (CRF) and γ-aminobutyric acid (GABA) synapti...

journal_title：Psychoneuroendocrinology

authors： Lamy CM,Beck SG

更新日期：2010-10-01 00:00:00

abstract：:The pathophysiology of depression has been associated to dysregulation of the hypothalamic-pituitary-adrenal axis and the use of salivary cortisol measures is increasingly being incorporated into research. The aim of the present study was to investigate whether salivary cortisol differs for patients with depression an...

journal_title：Psychoneuroendocrinology

authors： Knorr U,Vinberg M,Kessing LV,Wetterslev J

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Lack of social support and social exclusion are associated with adverse effects for mental and physical health. Additionally, women appear to be more vulnerable to social triggers of health disturbances. Activity of the hypothalamus-pituitary-adrenal-axis (HPA-axis) might play a key role in this context as i...

journal_title：Psychoneuroendocrinology

authors： Zöller C,Maroof P,Weik U,Deinzer R

更新日期：2010-10-01 00:00:00

abstract：:Remembering painful incidents has important adaptive value but may also contribute to clinical symptoms of posttraumatic stress disorder and chronic pain states. Because glucocorticoids are known to impair memory retrieval processes, we investigated whether cortisol affects recall of previously experienced pain in hea...

journal_title：Psychoneuroendocrinology

authors： Schwegler K,Ettlin D,Buser I,Klaghofer R,Goetzmann L,Buddeberg C,Alon E,Brügger M,de Quervain DJ

更新日期：2010-09-01 00:00:00

abstract：:In laboratory studies of individual differences in stress reactivity, cortisol responses are typically measured by comparing a prestress baseline with values obtained at the end of the stressor. In the present study, we measured cortisol in this manner on a stress day, but we also took samples on a second day when the...

journal_title：Psychoneuroendocrinology

authors： Lovallo WR,Farag NH,Vincent AS

更新日期：2010-09-01 00:00:00

abstract：:The current study examined intra-individual relationships between the cortisol awakening response (CAR) and state sleep-related and psychosocial variables in a pooled design study. 12 healthy female participants (age range: 22-41 years.) were examined on 12 study days each, occurring at three-day intervals. Quantitati...

journal_title：Psychoneuroendocrinology

authors： Stalder T,Evans P,Hucklebridge F,Clow A

更新日期：2010-09-01 00:00:00

abstract：:This study aimed to: (1) evaluate food craving and high-sweet-fat food craving across the menstrual cycle; (2) compare the craving and explicit/implicit emotional response to different food; and (3) investigate the reward sensitivity among PMDD and control groups. The PMDD group without treatment history and control g...

journal_title：Psychoneuroendocrinology

authors： Yen JY,Chang SJ,Ko CH,Yen CF,Chen CS,Yeh YC,Chen CC

更新日期：2010-09-01 00:00:00

abstract：:Prenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies. Although there are well-established sex-differences in the use of social communication (or 'pragmatic language') in humans, there has been limited investigation of the associ...

journal_title：Psychoneuroendocrinology

authors： Whitehouse AJ,Maybery MT,Hart R,Mattes E,Newnham JP,Sloboda DM,Stanley FJ,Hickey M

更新日期：2010-09-01 00:00:00

abstract：:Anabolic-androgenic steroid (AAS) abuse is widespread. Moreover, AAS are reinforcing, as shown by self-administration in rodents. However, the receptors that transduce the reinforcing effects of AAS are unclear. AAS may bind to classical nuclear androgen receptors (ARs) or membrane receptors. We used two approaches to...

journal_title：Psychoneuroendocrinology

authors： Sato SM,Johansen JA,Jordan CL,Wood RI

更新日期：2010-08-01 00:00:00

abstract：:Functional genomics strategies have been slow to penetrate research on human stress and coping, but recent conceptual advances have yielded a raft of new findings relating social and psychological conditions to broad alterations in human gene expression. This article reviews the field of human stress genomics, analyze...

journal_title：Psychoneuroendocrinology

authors： Cole SW

更新日期：2010-08-01 00:00:00

abstract：:A prenatal hypothyroid state is associated with behavioral abnormalities in adulthood. Wistar Kyoto (WKY) rats exhibit hypothyroidism and increased depressive and anxiety-like behaviors. Thus, the WKY could illuminate the mechanisms by which the reversal of developmental hypothyroidism in humans and animals results in...

journal_title：Psychoneuroendocrinology

authors： Shukla PK,Sittig LJ,Andrus BM,Schaffer DJ,Batra KK,Redei EE

更新日期：2010-07-01 00:00:00

abstract：:It is generally established that active-coping strategies and greater perceived control over pain are associated with improved pain-related outcomes; however, it remains unclear whether these factors independently or interactively influence adrenocortical function in reaction to a painful stimulus. The present study e...

journal_title：Psychoneuroendocrinology

authors： Bento SP,Goodin BR,Fabian LA,Page GG,Quinn NB,McGuire L

更新日期：2010-07-01 00:00:00

abstract：:Neurobiological research of obsessive-compulsive disorder (OCD) has rarely taken in account the context dependent evocation of obsessive-compulsive symptoms. To bypass this obstacle, this study investigated neurobiological parameters during a standardized disgust provocation paradigm in patients with OCD and healthy c...

journal_title：Psychoneuroendocrinology

authors： Fluitman SB,Denys DA,Heijnen CJ,Westenberg HG

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Subtle and inconsistent differences in hypothalamic-pituitary-adrenal (HPA) axis activity have been reported for patients with panic disorder. While these patients show little or no alterations in basal ACTH and cortisol levels, it has been hypothesized that HPA hyperresponsivity was a trait in panic patient...

journal_title：Psychoneuroendocrinology

authors： Petrowski K,Herold U,Joraschky P,Wittchen HU,Kirschbaum C

更新日期：2010-04-01 00:00:00

abstract：:Stress causes activation of the hypothalamic-pituitary-adrenal (HPA) axis and results in the secretion of corticosteroids, which facilitate behavioral adaptation and promote the termination of the stress response. These actions exerted by cortisol are mediated by two brain corticosteroid receptor types: the high affin...

journal_title：Psychoneuroendocrinology

authors： van Leeuwen N,Kumsta R,Entringer S,de Kloet ER,Zitman FG,DeRijk RH,Wüst S

更新日期：2010-04-01 00:00:00

abstract：:Many behavioral studies have found high-estrogen phases of the menstrual cycle to be associated with enhanced left-hemisphere processing and low-estrogen phases to be associated with better right-hemisphere processing. This study examined the changing of hemispheric asymmetry during the menstrual cycle by analyzing ev...

journal_title：Psychoneuroendocrinology

authors： Tillman GD

更新日期：2010-02-01 00:00:00

abstract：:This review highlights the progress made thus far in characterizing the behavioral and cellular mechanisms through which cannabinoids regulate energy homeostasis. We performed microstructural analysis of feeding behavior in gonadectomized guinea pigs and gonadally intact, transgenic CB1 receptor knockout mice to deter...

journal_title：Psychoneuroendocrinology

authors： Farhang B,Diaz S,Tang SL,Wagner EJ

更新日期：2009-12-01 00:00:00

abstract：:The differential exposure to circulating steroid hormones during brain development can have lasting consequences on brain function and behavior; therefore, the tight control of steroid hormone action within the developing brain is necessary for the expression of appropriate sex-typical behavior patterns later in life....

journal_title：Psychoneuroendocrinology

authors： Auger AP,Jessen HM

更新日期：2009-12-01 00:00:00

abstract：:Estrogen-induced synaptic plasticity was frequently shown by an increase of spines at apical dendrites of CA1 pyramidal neurons after systemic application of estradiol to ovariectomized rats. Surprisingly, exogenous application of estradiol to hippocampal cultures had no effect on spines and on spine synapses, althoug...

journal_title：Psychoneuroendocrinology

authors： Fester L,Zhou L,Voets C,Ossig C,Disteldorf E,Bläute F,Prange-Kiel J,Dudzinski D,Jarry H,Rune GM

更新日期：2009-12-01 00:00:00

abstract：:The research on thyroid hormones and personality traits is quite sparse and mainly focused on male forensic psychiatric populations in which the relationship between thyroid hormones and psychopathy and aggression-related personality traits has been reported. The suicidal temperament hypothesis suggests that certain p...

journal_title：Psychoneuroendocrinology

authors： Sinai C,Hirvikoski T,Vansvik ED,Nordström AL,Linder J,Nordström P,Jokinen J

更新日期：2009-11-01 00:00:00

abstract：:The neonatal nutritional environment is critical for programming the systems regulating body weight, and an inappropriate nutritional environment in early life can lead to overweight or obesity later on. In this study we demonstrate that changes to the neonatal nutritional environment, induced by changing the litter s...

journal_title：Psychoneuroendocrinology

authors： Spencer SJ,Tilbrook A

更新日期：2009-09-01 00:00:00

abstract：:The secretion of adrenal stress hormones in response to acute stress is known to affect learning and memory, particularly for emotionally arousing memory material. Here, we investigated whether stress-induced modulation of learning and memory performance depends on (i) the conceptual relatedness between the material t...

journal_title：Psychoneuroendocrinology

authors： Smeets T,Wolf OT,Giesbrecht T,Sijstermans K,Telgen S,Joëls M

更新日期：2009-09-01 00:00:00